Hayashida K, Takegawa R, Nishikimi M, et al. - Patients with out-of-hospital cardiac arrest (OHCA) easily experience hypothermia at lower ambient temperature. In animal models, an improved rate of successful return of spontaneous circulation is recorded in the presence of hypothermia. Researchers herein investigated whether lower temperature influences the impact of bystander cardiopulmonary resuscitation (CPR) on the raised odds of a favorable neurological outcome post-OHCA. Using the prospective, nationwide, Utstein registry, they examined data from 352,689 adult patients who experienced OHCA identifying the data of a total of 201,111 patients with OHCA for inclusion in the complete case analysis. Findings revealed correlation of bystander CPR with favorable neurological outcomes at lower temperatures. As the temperature decreased, there was an increase in the odds of a favorable outcome linked with bystander CPR.