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The increasing prevalence and adverse impact of morbid obesity in paediatric acute pancreatitis

Pediatric Obesity May 19, 2020

Thavamani A, Umapathi KK, Roy A, et al. - As obesity is increasingly prevalent in children, researchers used a large paediatric population‐based cohort to assess the effect of morbid obesity on the clinical outcomes of acute pancreatitis (AP). Using specific ICD‐9‐CM and ICD‐10‐CM codes, they analyzed the US Kids' Inpatient Database between years 2003 and 2016 to involve all patients (age ≤ 21 years) with a primary diagnosis of AP. Of 36,698 hospitalizations for paediatric AP, 1,275 were found to have morbid obesity. The proportion of children with morbid obesity among AP patients increased from 1.3% to 5.5% from 2003 to 2016. Cholelithiasis was viewed as a contributory aetiology to more than half (54%) of children with morbid obesity. The prevalence of severe AP in morbid obesity was significantly higher. According to multivariate analysis, morbid obesity was increasingly linked to severe AP, prolonged hospitalization, and higher hospital costs. There is a lack of other confounding comorbidities in children, unlike the adult population, and this national-level study indicates that morbid obesity independently predicts adverse clinical outcomes in paediatric AP.

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