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The impact of racial and ethnic health disparities in diabetes management on clinical outcomes: A reinforcement learning analysis of health inequity among youth and young adults in the SEARCH for Diabetes in Youth Study

Diabetes Care Nov 07, 2021

Kahkoska AR, Pokaprakarn T, Alexander GR, et al. - A part of but not all disparities in glycemic control between non-White and White youth and young adults (YYA) were explained by mathematically modeling an equalized distribution of type 1 diabetes (T1D) self-management tools and technology. This highlights the complexity of race and ethnicity-based health inequity.

  • Disparities in population-level glycemic control and occurrence of diabetes complications were estimated, given a theoretical scenario wherein non-White YYA suffering from T1D undergo and follow an equal distribution of diabetes treatment regimens as non-Hispanic White YYA.

  • Using longitudinal data, this study involved 978 YYA, 47.5% were female and 77.5% were non-Hispanic White, with a mean age of 12.8 ± 2.4 years at diagnosis.

  • Mean hemoglobin A 1c across visits reduced by 0.33% within the non-White subgroup if they received the distribution of diabetes treatment regimens of the White subgroup, accounting for ∼35% of the estimated disparity between the two subgroups.

  • A lower risk of diabetic retinopathy, diabetic kidney disease, and peripheral neuropathy was noted in the non-White subgroup if they received the White youth treatment regimen distribution, although the low proportion of YYA who experienced complications limited statistical power for risk estimations.

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