Suzuki A, Ando M, Kimura T, et al. - Researchers undertook a prospective randomized controlled crossover trial to investigate whether high-flow nasal cannula (HFNC) oxygen therapy compared with conventional oxygen therapy would afford a superior option for improving exercise capacity in fibrotic interstitial lung disease (FILD) patients. In this study, experts applied a high-intensity constant work-rate endurance test using HFNC (50 L/min, FiO₂ 0.5) and a venturi mask (VM) (15 L/min, FiO₂ 0.5) for oxygen delivery in FILD patients. Overall 711 patients were screened and randomization involved 20 eligible patients. The trial was completed by all patients. Findings revealed that in terms of improving exercise capacity in FILD, HFNC did not afford a superior efficacy than VM, but maybe useful if the settings match.