Heyduck A, Brosch S, Pickhard A, et al. - Researchers conducted this prospective monocentric study to determine the efficiency of laryngovideostroboscopy (LVS) in detecting premalignancies of the vocal fold and early glottic cancer, as well as to assess the recovery rate of the mucosal membrane on the vocal fold after surgical intervention by LVS. The sample consisted of 159 patients with leukoplakia of the vocal folds and 50 healthy controls. Patients with a history of laryngosurgery, radiotherapy, or laryngeal scarring were not eligible. LVS is a reliable method for detecting early glottic carcinoma and high-risk premalignancy carcinoma in situ (CIS). Even when a definitive distinction between severe intraepithelial neoplasia I and II cannot be made, the invasive character of a CIS and invasive glottic carcinoma can be identified. Strobosopic signs of abnormal amplitude and/or mucosal waves, especially phoniatric halt, are an early indicator of CIS or invasive carcinoma.