Akhgar A, Pouryousefi T, Nejati A, et al. - Researchers examined the efficacy of intravenous (IV) lidocaine vs IV morphine in acute pain management in the emergency department (ED). In this double-blind randomized clinical trial on adult (18–64 year) patients with right upper abdominal pain suspected of biliary colic who needed pain management, IV lidocaine (5 cc = 100 mg) or morphine sulfate (5 cc = 5 mg) was randomly assigned to the participants. Participants were 104 patients (49 men and 55 women) with right upper abdominal pain suspected of biliary colic who needed pain management. Per outcomes, IV lidocaine can be a good option for managing pain in biliary colic and can ameliorate pain in less time than morphine sulfate (in 10 min) without adding significant side effects. However, the primary outcome of this study was the comparison of these two drugs after 60 min of drug administration in pain reduction which indicated no significant difference between two groups.