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The effects of opioid use on thromboembolic complications, readmission rates, and 90-day episode of care costs after total hip arthroplasty

Journal of Arthroplasty Mar 25, 2020

Sodhi N, Anis HK, Acuña AJ, et al. - This study was undertaken to evaluate whether opioid use disorder (OUD) individuals are at greater odds than non–opioid use disorder individuals in developing thromboembolic complications, readmission rates; and costs of care. Researchers distinguished all individuals with a 90-day history of OUD before total hip arthroplasty (THA) from a national database. Individuals were compared 1:5 to controls by age, gender, Elixhauser Comorbidity Index scores, and high-risk medical comorbidities, yielding 38,821 individuals with (n = 6,398) and without (n = 31,883) OUD. They conducted multivariate logistic regression analyses to correlate the risks of developing venous thromboembolism (deep vein thrombosis and/or pulmonary embolism) 90 days after the index procedure, 90-day readmission rates, and total global 90-day episode of care costs. The outcomes of this study displayed that primary THA individuals with a history of OUD are at greater risks for thromboembolic complications, readmissions, and higher costs of care in the 90-day postoperative period.

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