Jiang S, et al. - The effects of low-dose human chorionic gonadotropin (hCG) combined with human menopausal gonadotropin (HMG) protocol on cycle characteristics and outcomes of infertile women with hypogonadotropic hypogonadism (HH) undergoing ovarian stimulation for in vitro fertilization (IVF) were explored in this study. For HH women undergoing ovarian stimulation in IVF, low-dose hCG combined with HMG was a feasible protocol, providing favourable cycle characteristics and pregnancy rates. While the hCG dose and embryo quality were not positively correlated, low-dose hCG reduced HMG duration. The outcomes of frozen- thawed embryo transfer (FET) were similar to embryo transfer (ET), which gave a greater chance of success from IVF in the low-responders with HH.