Kiburg KV, MacIsaac AI, McCluskey GE, et al. - A greater extent of coronary artery disease (CAD) was found in patients with diabetes vs those without Type 2 Diabetes Mellitus (T2DM), but this CAD burden was significantly reduced by preventative medication use.

• From a coronary angiography database, 1,421 patients with T2DM and 1,421 without T2DM were matched on propensity score.

• More extensive CAD in T2DM patients was seen in 2018 relative to 2013 ((adjusted odds ratio) adjOR: 2.06 95% C.I. 1.38, 2.07), but this risk seemed to be decreased in 2019.

• Significantly higher use of medications was evident in T2DM cases vs patients without diabetes [statins used by 69.8% vs 46.6%, renin-angiotensin system (RAS) inhibitors: 64.0% vs 49.0%, and anti-platelet drugs: 64.0% vs 49.9%].

• As in the full matched sample, more extensive CAD was found in patients with diabetes (adjOR: 1.32).

• However, post-adjustment for use of RAS inhibitors, statins and anticoagulants, extent of CAD did not differ between patients with and without diabetes (adjOR: 1.14).