Cimino AM, Veazey GC, McMurtrie JT, et al. - This study was sought to synthesize the clinical outcome data of pre-operative and post-operative corticosteroid injections and their effect on rotator cuff repairs. Researchers carried out a systematic review to distinguish studies that reported the results or clinical outcomes of rotator cuff repairs in patients receiving either preo-perative or post-operative corticosteroid injections. The searches were conducted using MEDLINE, Google Scholar, and Embase, and studies were chosen following PRISMA guidelines. They enrolled 11 studies with data for 176,352 shoulders. They included six studies involving 175,256 shoulders with data regarding pre-operative CIs and four studies involving 1,096 shoulders with data regarding post-operative CIs. The outcomes of this research demonstrate that corticosteroid injections provide benefit by relieving pain and improving functional outcome scores. Nevertheless, repeated pre-operative CIs may elevate retear rates and the likelihood of revision surgery. It was demonstrated that a lower frequency of CI and longer pre-operative waiting period after CI should be recognized to reduce such risks. After RCR, post-operative CIs several weeks do not seem to elevate retear rates.