Nasiri S, Azhari V, Bidari‐Zerehpoosh F, et al. - Researchers sought to clarify the expression of p63, p16 and p53 proteins in seborrheic keratosis (SK), actinic keratosis (AK) and Bowen’s disease (BD) and assess the effectiveness of these markers in order to distinguish between the aforementioned lesions. In total, 46 cases were obtained (15 SK, 16 AK and 15 BD) and stained for p63, p16 and p53. The finding shows that p16 and p53 are useful markers in distinguishing AK and BD according to the involvement and sparing of basal keratinocytes, respectively.