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The course of subjective and objective chemosensory dysfunction in hospitalized patients with COVID-19: A 6-month follow-up

European Archives of Oto-Rhino-Laryngology Apr 14, 2021

Bertlich M, Stihl C, Lüsebrink E, et al. - Researchers performed a retrospective chart review of the long-term course of chemosensory dysfunction following SARS-CoV-2 infection. Twenty-three SARS-CoV-2-positive patients diagnosed with subjective hyposmia in spring 2020 (out of 57 positive patients, 40.3%) were compared with SARS-CoV-2-positive patients without hyposmia (n = 19) and SARS-CoV-2-negative patients (n = 14). The Brief Smell Identification Test (BSIT), Taste Strips (TS), Visual Analogue Scales (VAS), and the SNOT-22 were used to assess chemosensory function. The initial hyposmia cohort was also examined at 8 weeks and 6 months after the initial examination. No differences were found between the SARS-CoV-2-positive cohort without hyposmia and negative controls in terms of BSIT, TS or VAS, however, the SNOT-22 was significantly elevated. Patients with SARS-CoV-2 that have a subjectively impaired chemosensory function often perform poorly in objective measurements. Approximately 70% of SARS-CoV-2 patients with olfactory dysfunction recover quickly, while the remaining patients continue to have significant impairment 6 months after infection.

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