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The co-occurrence of frailty (accumulation of functional deficits) and depressive symptoms, and its effect on mortality in older adults: A longitudinal study

Clinical Interventions in Aging Oct 04, 2019

Chang HY, Fang HL, Ting TT, et al. - Using the Taiwan Longitudinal Study of Aging, researchers investigated the co-existence of frailty and depressive symptoms in late life. They also looked at the likelihood of symptom reversal, their reciprocal link, and the influences on mortality. They used the Center for Epidemiologic Studies Depression Scale to measure depressive symptoms. They reported higher mortality in correlation with the coexistence of frailty and depressive symptoms. The likelihood of reversal to a better state was lower in people with depressive symptoms. Although current frailty was predicted by previous depression score but the coefficient was smaller compared with that of earlier frailty. The current depression score was predicted by previous frailty, and the coefficient was stronger compared with that of previous depression. Overall, increased mortality and reduced likelihood of reversal were observed in relation to the presence of depressive symptoms in the frail older adults.
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