Rasheed H, Zheng J, Rees J, et al. - Since there is lack of clarity on the causal nature of the observed links between serum lipids and apolipoproteins and kidney function, researchers assessed the causal impacts of serum lipids and apolipoproteins on renal function, reflected by the glomerular-filtration rate estimated using creatinine or cystatin C and the urinary albumin-to-creatinine ratio (UACR). For this purpose, they used two-sample and multivariable Mendelian randomization (MR). The MR estimates generated herein indicate that serum lipid and apolipoprotein levels did not induce substantial alterations in renal function. Further inquiry is warranted for a likely weak impact of higher atherogenic lipids on elevated estimated glomerular-filtration rate and UACR. Processes resulting in higher UACR may cause more atherogenic lipid levels.