• Profile
Close

The association of polymorphisms in TNF and ankylosing spondylitis in common population: A meta-analysis

European Spine Journal Apr 25, 2021

Hu N, Chen X, Wang S, et al. - This study was sought to conduct a meta-analysis based on the evidence available from the literature up-to-date to further clarify this relationship. Researchers carried out to search the PubMed, Embase, and Cochrane databases (up to March 2020). They used pooled and individual odds ratios with 95% confidence intervals of the minor allele of each locus to evaluate the relationships between TNF polymorphisms and ankylosing spondylitis in different ethnicities in a common population. This meta-analysis enrolled 17 studies, consisting of seven European studies, eight East Asian studies, and two Latin-American studies, were included. The meta-analysis implies that TNF-α polymorphisms at positions − 238, − 308, − 850, − 1031, and rs769178 could have an influence on ankylosing spondylitis susceptibility in the total population. No association was found between TNF-376, TNF-857, TNF-863 polymorphisms, and ankylosing spondylitis. In the subgroups, some results are not consistent with those in the total population.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay