Savji N, et al. - Researchers assessed the links of obesity and cardiometabolic traits with incident heart failure with preserved vs reduced ejection fraction (HFpEF vs HFrEF). They examined men and women, given known sex differences in HF subtype. Participants were 22,681 subjects from 4 community-based cohorts followed for incident HFpEF vs HFrEF (ejection fraction ≥ 50% vs < 50%). They found a stronger association of obesity and related cardiometabolic traits (including insulin resistance) with the risk of future HFpEF vs HFrEF. Women seemed to have particularly pronounced differential risk of HFpEF with obesity, which may be the cause of sex differences in HF subtypes.