Maheshwari K, et al. - Researchers investigated if hypotension during non-cardiac surgery, before and after skin incision, is similarly related to postoperative kidney injury. They examined 42,825 patients undergoing elective non-cardiac surgery, for the link between mean arterial pressure < 65 mmHg and postoperative kidney injury. The occurrence of intra-operative hypotension was reported in 30,423 (71%) patients: 22,569 (53%) patients before skin incision; and 24,102 (56%) patients after incision. For each doubling of the duration of hypotension, 1.05 (1.02–1.07) was documented as odds ratio (95%CI) for acute kidney injury. Attributed to anaesthetic management, the occurrence of a substantial fraction of all hypotension was reported prior to surgical incision. Assuming that, mean arterial pressure < 65 mmHg is, at least in part, causally related to postoperative kidney injury, anaesthetists were recommended to avoid mean arterial pressure < 65 mmHg during surgery, especially after induction.