Park J, Kim G, Kim H, et al. - Findings revealed that hepatic steatosis and/or advanced fibrosis as evaluated via fatty liver index (FLI) and BARD score was significantly related to the risk of heart failure (HF) and mortality.

• This study included 778,739 people without HF and 7,445 patients with pre-existing HF aged 40 to 80 years who participated in a national health check-up.

• Applying cutoff values for FLI and BARD score, presence of hepatic steatosis and advanced hepatic fibrosis was ascertained.

• An FLI ≥ 60 was associated with elevated risk for incident heart failure (iHF) (hazard ratio [HR], 1.30), hospitalized HF (hHF) (HR 1.54), all-cause death (HR 1.62), and cardiovascular (CV) death (HR 1.41) in the general population and hHF (HR 1.26) and all-cause death (HR 1.54) in the HF patient group, vs an FLI < 20.

• In nonalcoholic fatty liver disease cases, advanced liver fibrosis was related to elevated risk for iHF, hHF, and all-cause death in the general population and all-cause mortality and CV mortality in the HF patient group.