Weldegiorgis TZ, et al. - In the 2764 middle-aged and elderly Chinese population (aged above 50 years), researchers studied the connection between serum 25-hydroxyvitamin D [(25-(OH)D] concentrations and metabolic syndrome (MetS). Investigators found that serum 25-(OH) D levels in the MetS group were significantly lower than those in men without MetS. A negative correlation was reported between the higher quartiles of serum 25-(OH) D levels and the presence of MetS among men. Even after adjusting for potential confounders including, age, cigarette status, alcohol use, physical activity, low-density lipoprotein, creatinine, and total serum cholesterol, the link between serum 25-(OH)D levels and the prevalence of MetS persisted. According to this cross-sectional study, decreased serum 25-(OH) D level in the middle-aged men was inversely associated with MetS.