Erhunmwunsee L, Wing SE, Shen J, et al. - Researchers used a retrospective cohort to determine if residing in polluted neighborhoods was related to somatic mutations linked with lower survival rates, i.e TP53 mutations, among non-small cell lung cancer (NSCLC) patients (n = 478) treated at a comprehensive cancer center between 2015 and 2018. They noted somatic TP53 mutations were present in 277 patients (58%). Of those, 45% resided in neighborhoods with "moderate" Environmental Protection Agency-defined PM2.5 (particulate matter) exposure, vs 39% of patients without TP53 mutations. Findings revealed elevated odds of having a TP53-mutated NSCLC in regions with higher PM2.5 exposure, after controlling for individual- and neighborhood-level confounders.