Lemes IR, Pinto RZ, Turi Lynch BC, et al. - Researchers sought to determine if and how leisure-time physical activity (LTPA) was associated with low back pain (LBP) in adults from primary care settings, in this observational cross-sectional study. They also investigated the impact of sedentary behavior on this link. Information on physical activity, sedentary behavior (sitting time), LBP, body mass index (BMI), and chronic diseases was evaluated via face-to-face interviews, physical assessment, and medical records. Findings demonstrated an inverse link of LTPA with the prevalence of LBP among adults from primary care. Also, results showed an impact of sedentary behavior and BMI on this link. Active participants were 33% less likely to have LBP vs those insufficiently active. A significant association was found for active participants who spent less than 3 hours/day sitting but not for those who spent 3 hours/day or more in sedentary activities. An inverse association of LTPA with LBP was observed in obese participants, but not in those with normal BMI and overweight.