de Bakker M, den Uijl I, ter Hoeve N, et al. - Researchers design the prospective cohort study at outpatient cardiac rehabilitation (CR) center in order to investigate the strength of the correlation between exercise capacity and health-related quality of life(HRQOL) during and following CR in individuals with acute coronary syndrome (ACS) (n = 607), who completed CR. At baseline(pre-CR), the six-minute walk test(6MWT) was done to discover exercise capacity, and the MacNew Heart Disease Health-related Quality of Life questionnaire was utilized to assess HRQOL. The mean age was 58 years and 82% were male. Mean 6MWT distance and the global, physical, emotional and social domains of HRQOL enhanced meaningfully during CR and proceeded to improve during follow-up post-CR. It was found that better exercise capacity was notably correlated with greater scores on the global and physical domains of HRQOL, irrespective of the timing relative to CR, albeit these correlations were weak. Therefore, CR programs in secondary prevention shall continue to strive at improving both HRQOL and exercise capacity.