Malling GMH, Gronemann FH, Vassard D, et al. - Among both women in assisted reproductive technology (ART) treatment and women without ART treatment, researchers examined the effects of antidepressant use on cumulative live birth rates (CLBR) and number of initiated treatment cycles per woman. In addition, they examined whether the risk of initiating use of antidepressants is higher in women undergoing ART treatment vs women not having undergone ART and if the risk for postpartum use of antidepressants was higher among mothers having used ART treatment compared with those not having used ART treatment. In this Danish nation-wide register-based cohort study, researchers included all women in ART treatment between 1995 through 2009 as well as an age-matched comparison group of women not having started ART treatment. In general, no higher risk of initiating use of antidepressants was evident among women undergoing ART treatment vs an age-matched comparison group not treated with ART. However, fewer ART treatments and lower CLBR were reported in women with antidepressant medication use prior to ART. Based on this study, they recommend clinicians to be aware of the fact that women conceiving after ART treatment might experience an increased level of psychological strain during the postpartum period relative to mothers who conceived without ART.