Skov‐Jeppesen K, Hepp N, Oeke J, et al. - Researchers ascertained if the changes in bone turnover after meal intake and after glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐2 (GLP‐2) injections, respectively, are mediated via a reduction in parathyroid hormone (PTH) secretion. A randomized crossover design was used to assess this in female hypoparathyroidism patients who were given a standardized liquid mixed‐meal test (n = 7) followed by a peptide injection test (n = 4). The results indicate that the GIP-induced effect on bone turnover could be mediated directly by GIPR expressed in osteoblasts and osteoclasts and that this could happen without the involvement of PTH. The effect of GLP2 on bone turnover, on the other hand, appears to be dependent on changes in PTH and may be mediated by GLP‐2R in the parathyroid gland.