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The analysis of anxiety and depression in different stages of in vitro fertilization-embryo transfer in couples in China

Neuropsychiatric Disease and Treatment Feb 28, 2021

Liu YF, Fu Z, Chen SW, et al. - Infertile Chinese couples were examined in diverse stages of in vitro fertilization-embryo transfer (IVF-ET) for their differences in anxiety and depression and correlations with the IVF-ET outcomes. For this study, researchers randomly selected a total of 247 couples that were undergoing IVF-ET. They completed self-designed questionnaires, the Self-Rating Anxiety Scale, and the Self-Rating Depression Scale on the day they initiated their treatment (T1), the day human chorionic gonadotropin was administered (T2), and 4 days following the embryo transfer (T3). In women, age was identified to have an impact on the anxiety and depression. In men, anxiety and depression were linked with male infertility type and the cause of infertility. The incidence of anxiety in women in the T1, T2, and T3 stages was 29.96%, 44.94%, and 17.81%, respectively. The anxiety scores of women were 46.14 ± 8.37, 50.83 ± 8.50, and 44.09 ± 8.17, respectively, and they were significantly higher than those of men. Findings revealed differences in the incidence of anxiety and depression in infertile couples in diverse stages of IVF-ET, especially in women. The anxiety and depression of infertile couples in the process of IVF-ET appeared to have no correlation with the outcome of assisted pregnancy

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