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Ten-year results of concentrated autologous bone marrow aspirate transplantation for osteonecrosis of the femoral head: A retrospective study

BMC Musculoskeletal Disorders Sep 14, 2019

Tomaru Y, Yoshioka T, Sugaya H, et al. - Researchers describe the long-term outcomes of concentrated autologous bone marrow aspirate transplantation (CABMAT) treatment, a joint-preserving treatment for osteonecrosis of the femoral head (ONFH). Participants were 69 patients (109 hips) with idiopathic ONFH managed with CABMAT between April 2003 and April 2008. For these patients, the demographic and treatment data were retrospectively assembled and examined. A 10-year follow-up was completed by 44 patients (21 men, 23 women, 80 hips). The overall rate of conversion to total hip arthroplasty (THA) was estimated to be 34% (27/80 hips). A significant correlation of preoperative stage of ONFH and the body mass index with conversion to THA was revealed in a multivariate regression analysis. They grouped 43 hips (of 80) as belonging to the pre-collapse stage (ie, stages 1 or 2). The overall collapse rate of these hips was 49% (21/43) and the THA-conversion rate was 14% (6/43). This long-term analysis revealed the utility of the minimally invasive and feasible CABMAT therapy to serve as one of a joint-preserving treatment for ONFH.
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