• Profile
Close

Temporal trends in the level and decline of cognition and disability in an elderly population: The PAQUID Study

American Journal of Epidemiology Jun 20, 2018

Grasset L, et al. - Considering the declining trends in dementia incidence, researchers compared the cognitive and functional evolution of two “generations” separated by 10 years. Furthermore, they evaluated the impact of specific risk factors on this evolution. They conducted this study on two “generations” of elderly individuals aged 78-88 years, who were included 10 years apart in the Personnes Agées QUID (PAQUID) cohort (France) (n = 612 in 1991-92 and n = 628 in 2001-02) and followed-up for 12 years, with assessments of cognition and disability. The second generation showed higher performances at baseline on four cognitive tests (from p < 0.005). Improvement in educational level mostly explains the differences in global cognition, verbal fluency, and processing speed, but not in working memory. Less cognitive decline in verbal fluency and working memory was also observed among the second generation elderly. The second generation showed a lower progression in disability over the follow-up period compared to the first one. Improvements in educational level could partially contribute to the improved cognitive state of this elderly population.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay