Guedeney P, et al. - In 2,653 patients undergoing elective percutaneous coronary intervention (PCI) between January 2010 and May 2016, researchers studied the link between adherence to guideline-recommended statin therapy (GRST) and the rate of residual cholesterol risk (RCR) at follow-up. The definition of GRST included high-intensity statin (HIS) therapy for patients ≤75 years old and moderate-intensity statin (MIS) or HIS therapy for patients >75 years. HIS resulting in <50% decrease in LDL-C or MIS resulting in <30% decrease for statin-naive patients and LDL-C > 70mg/dL for non-statin-naive patients were the parameters that defined RCR at follow-up. Female gender, prior myocardial infarction, smoking, and higher LDL-C level at baseline conferred risk for RCR at follow-up. An increased adjusted risk of death within one-year of the second LDL-C measurement was noted in relation to the presence of RCR. Over time, improvement in the rate of GRST at discharge was significant, but no substantial change has been reported in the prevalence of RCR at follow-up.