Velagapudi P, et al. - Researchers analyzed temporal trends in length of stay (LOS) and identified independent predictors of longer LOS (LOS >3 days) in patients who underwent primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI), using the 2005 to 2014 National Inpatient Sample databases and multivariable linear and logistic regression models. All hospitalizations (in which patients were discharged home alive) in patients ≥18 years of age were included. Over time, a substantial reduction has been noted in the number of hospitalizations for PPCI for STEMI that lasted over 3 days (31.9% in 2005 to 16.9% in 2014; P<0.001) and it was suggested that targeting strategies to reduce procedure-related risk may translate into shorter LOS. Factors that independently associated with longer LOS included patient demographics, comorbidities, hospital region, use of mechanical circulatory support, and peri-procedural complications.