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Tachysystole and risk of cesarean section after labor induction using misoprostol: A cohort study

European Journal of Obstetrics & Gynecology and Reproductive Biology Apr 22, 2020

Sichitiu J, Vial Y, Panchaud A, et al. - Researchers examined if there is a correlation between tachysystole and an increased risk of cesarean section or unfavorable maternal or neonatal outcomes following induction of labor by misoprostol vaginal inserts. In this retrospective cohort study, 446 women over 37 weeks of gestation admitted for labor induction by misoprostol vaginal inserts between May 2016 and May 2017 were assessed. Among these, tachysystole occurred in a total of 140 women (31.4%). The analysis revealed no correlation of tachysystole with an increased risk of cesarean section after induction of labor by misoprostol vaginal inserts. Mothers who did and did not experience tachysystole were similar concerning neonatal (Apgar score < 7 at 5 minutes, umbilical cord artery pH < 7.10, neonatal intensive care unit admission) and maternal outcomes. Probably insufficient impact of excessive uterine activity, defined by the frequency of uterine contraction alone, was evident on the fetal wellbeing.

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