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Systolic blood pressure variability following endovascular thrombectomy and clinical outcome in acute ischemic stroke: A meta‐analysis

Acta Neurologica Scandinavica Jun 15, 2021

Nepal G, Shrestha GS, Shing YK, et al. - Studies have described correlation of blood pressure variability (BPV) with the outcome of acute ischemic stroke (AIS) after endovascular thrombectomy (EVT). Researchers aimed at determining the correlation of the stroke outcome with specific short-term BPV parameters via performing a systematic review and meta-analysis. They identified a total of 11 studies for inclusion in meta-analysis, which comprised 3,520 patients who underwent EVT. Observations revealed lower odds of achieving good functional outcome at 3 months; that is, modified Rankin Scale (mRS) score ≤ 2, in correlation with standard deviation, coefficient of Variation, successive Variation of systolic blood pressure. However, there was no correlation of high BPV with symptomatic intracranial hemorrhage and all-cause mortality at 90 days. The association of BPV and early neurological deterioration was inconclusive. The available data overall suggest that short-term systolic BPV is indicative of the clinical outcome of patients following EVT in AIS.

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