Frazzoni L, La Marca M, Radaelli F, et al. - By performing a systematic review, researchers sought to determine the impact of colonoscopy appropriateness in terms of producing additional diagnoses and sparing unnecessary exams. They included 21 studies (19,822 patients) for this analysis. In 15,162 (71%) patients, colonoscopy was appropriate. Appropriateness was correlated with significantly greater chances of relevant findings (34% vs 18%), CRC (7% vs 2%) and IBD (6% vs 4%). Per 100 patients, on average, colonoscopy with appropriate indication discovers 15 more relevant findings, five more CRCs and three more diagnoses of IBD. They suggest appropriateness criteria as valuable, although it is combined with clinical evaluation of the patient.