Sherrell H, et al. - Researchers ascertained the utility of maternal Placental Growth Factor (PlGF) when measured in late pregnancy (>20 weeks) as a predictor of adverse obstetric and perinatal outcomes in this systematic review. In late pregnancy, low maternal PlGF levels are observed to have a strong association with small for gestational age (SGA). In relation to PlGF and the prediction of other adverse intrapartum and perinatal outcomes, no consistent findings were evident, however, a consistent association between low PlGF levels and caesarean section (CS) was noted for fetal compromise, NICU admission, and stillbirth. The review suggests that for the prediction of adverse outcomes, the use of PlGF is promising. It seems that using PlGF, in combination with other biomarkers or biophysical measures of fetal well-being, may potentially enhance its predictive value.