Dueland S, Yaqub S, Syversveen T, et al. - Researchers aimed at comparing patients with colorectal cancer and high liver metastasis tumor load who were treated with liver transplant vs those who underwent PVE and liver resection, in terms of their overall survival (OS). In this comparative effectiveness research study, 50 patients with colorectal cancer and widespread liver metastases who underwent liver transplant and 53 matched patients who underwent portal vein embolization and liver resection were included. Patients with left-sided primary tumor and liver grafts had overall survival exceeding overall survival of those treated with portal vein embolization and liver resection. Based on findings, they suggest considering highly selected patients with colorectal cancer and nonresectable liver metastases for liver transplant in prospective studies.