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Survival and right ventricular function after surgical management of acute pulmonary embolism

Journal of the American College of Cardiology Aug 20, 2020

Goldberg JB, Spevack DM, Ahsan S, et al. - Whether surgical management of acute pulmonary embolism (PE) is safe and efficacious, was investigated. Researchers compared surgical embolectomy and/or venoarterial extracorporeal membrane oxygenation, between 2005 and 2019, for massive PE (MPE) vs high-risk submassive PE (SMPE). This analysis involved 136 patients with PE (92 with SMPE and 44 with MPE). Improvement in right ventricular (RV) function was evident, as measured by central venous pressure, pulmonary artery systolic pressure, RV/left ventricular ratio, and fractional area change. Mortality was estimated to be 4.4%. Morbidity and mortality were shown to be highly related to preoperative cardiopulmonary resuscitation, as revealed in subgroup analysis. Overall, experts concluded that it is safe to surgically treat patients with MPE and high-risk SMPE, and surgical management is a highly effective means to achieve RV recovery in these patients.

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