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Survival and predictors of outcome amongst patients with decompensated liver disease in a non-liver transplant ICU. Pessimism is historical and unjustified

Internal Medicine Journal Mar 20, 2019

Sadick V, et al. - In this retrospective observational study, conducted in a tertiary, non-liver transplant unit in Sydney, Australia, researchers assessed 63 candidates to examine survival as well as predictors of outcome among subjects with decompensated liver disease between 2013 and 2017. They recorded 37% as the overall hospital mortality. They observed a significant difference in survival based on presenting diagnosis, with better survival among patients diagnosed with hepatic encephalopathy on ICU admission. No difference in survival was noticed based on the etiology of liver disease. They reported 4% mortality in outpatients with no organ failure, whereas 52% is the mortality recorded in those with ≥3 organs in failure. They preferred the ICU prognostic Sequential Organ Failure Assessment (SOFA) score in predicting the short-term consequences vs liver prognostic scores.

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