Surgical management of symptomatic apical pelvic organ prolapse: A systematic review and meta-analysis
Obstetrics and Gynecology May 28, 2021
Larouche M, et al. - Researchers conducted a systematic review investigating objective and subjective success and complications of apical suspensions for symptomatic uterine or vaginal vault pelvic organ prolapse (POP). Searching MEDLINE, CENTRAL, ClinicalTrials.gov, and EMBASE (2002–2019), they identified 2,665 records, from which included were randomized controlled trials and comparative studies of interventions with or without hysterectomy, including abdominal apical reconstruction through open, laparoscopic, or robotic approaches and vaginal apical reconstructions. The review was performed including 62 articles (N = 22,792) and meta-analyses included 50 studies. Higher risk of overall and apical anatomic recurrence was reported in correlation with vaginal suspensions vs sacrocolpopexy (RR 1.82, 95% CI 1.22–2.74 and RR 2.70, 95% CI 1.33–5.50) (moderate), whereas less overall and posterior anatomic recurrence was recorded with minimally invasive sacrocolpopexy compared with open sacrocolpopexy (RR 0.59, 95% CI 0.47–0.75 and RR 0.59, 95% CI 0.44–0.80, respectively) (low). Overall outcomes revealed variations in anatomic outcomes. However, there was similarity in subjective outcomes and complications for apical POP procedures at 1–5 years.
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