Ho H, Williamson C, Regis SM, et al. - Although survival improves in correlation with lung cancer screening with low-dose chest computed tomography (LCS), concerns remain regarding overdiagnosis and unnecessary interventions. Researchers here assessed their LCS program to ascertain the rate of surgery and invasive procedures for non-malignant disease. From January 2012 through June 2017, they screened 3,280 patients; of these, 345 (10.5%) had Lung-suspicious findings (Lung-RADS® 4). Overall, 0.43% of LCS patients had surgical resection for benign disease. A combined incidence of only 0.95% was observed for any invasive diagnostic or therapeutic intervention, including surgical resection, for benign disease. They rarely saw periprocedural complications. These results suggest the concern over unnecessary interventions and this should not impede adoption of LCS. To maintain an appropriate rate of interventions in LCS, they suggest a multidisciplinary team approach, including thoracic surgeons, is critical.