Rader F, et al. - Researchers evaluated participants of the Dallas Heart Study—including non-Hispanic black (n = 1,262) and white (n = 927) adults—to compare associations between out-of-office and clinic blood pressure (BP) measurement with left ventricular hypertrophy using cardiac MRI in this cross-sectional analysis. They performed multivariable-adjusted analyses of treated and untreated participants, which revealed that left ventricular hypertrophy was more strongly determined by out-of-office BP than clinic BP. Independent determinants of hypertrophy also included non-Hispanic black race/ethnicity, treatment status, and lower left ventricular ejection fraction. Vital information, beyond that offered by clinic BP evaluation alone, was obtained via protocol-driven supervised out-of-office BP monitoring. As a preventive strategy against the development of hypertensive heart disease, particularly in high-risk black adults, the significance of hypertension management programs outside the medical office was emphasized.