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Suicide risk in Medicare patients with schizophrenia across the life span

JAMA Jun 01, 2021

Olfson M, Stroup TS, Huang C, et al. - Researchers aimed at describing suicide mortality rates and correlates among adults with schizophrenia across the life span. In addition, they investigated standardized mortality ratios (SMRs) for suicide among these adults compared with the general US population. From the Medicare program, they identified five national retrospective longitudinal cohorts of patients with schizophrenia by age from January 1, 2007, to December 31, 2016: 18 to 34, 35 to 44, 45 to 54, 55 to 64, and 65 years or older. The National Death Index was employed to obtain death record information. This cohort study of 668,836 patients with schizophrenia and Medicare coverage revealed higher risk of suicide when compared with the general US population. The risk was noted to be the highest among those aged 18 to 34 years and lowest among those 65 years and older. In young adults, a recent history of suicide attempts or self-harm, suicide ideation, and substance use disorders linked with suicide risk. Considering these findings, researchers emphasize focusing on younger adults with suicidal symptoms and substance use disorders when making suicide prevention efforts for individuals with schizophrenia.

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