Malik VS – The goal of this research was to offer an update on the epidemiological and trial evidence linking intake of sugar sweetened beverages (SSB) to cardiometabolic outcomes. Researchers found conclusive evidence that was supportive of a causative role of SSB in association with weight gain and risk of type 2 diabetes (T2D) and coronary heart disease (CHD) that was independent of weight. Therefore, in order to improve the cardiometabolic health of individuals and populations, continued efforts to reduce intake of SSB should be encouraged.

Recent findings

• Researchers found that the weight of the evidence from prospective cohort studies supported a strong positive link between intake of SSB and weight gain and risk type 2 diabetes (T2D) and coronary heart disease (CHD) that was independent of adiposity.
• Data reported that associations with stroke were less clear and indicative of greater risk in women than men.
• Additionally, mechanistic support for associations with T2D and CHD was provided by short-term trials of SSB and markers of cardiometabolic risk including lipids, glucose, blood pressure, and inflammatory cytokines.
• As per observations, putative underlying mechanisms included adverse glycemic effects and increased hepatic metabolism of fructose.