Hur J, Otegbeye E, Joh HK, et al. - In the present study, the researchers sought to explore the connection between intake of sweetened beverages in adulthood and adolescence, with a particular focus on sugar-sweetened beverages (SSBs), and risk of early-onset colorectal cancer (EO-CRC). In the Nurses’ Health Study II (1991–2015), they prospectively examined the correlation of SSB intake in adulthood and adolescence with EO-CRC risk among 95,464 women who had reported adulthood beverage intake utilizing validated food frequency questionnaires every 4 years. One hundred nine EO-CRC cases were documented. Higher SSB intake in adulthood and adolescence was linked to an increased risk of EO-CRC in women. Reducing SSB consumption among adolescents and young adults may be a viable strategy for mitigating the growing burden of EO-CRC.