Kheterpal S, Vaughn MT, Dubovoy TZ, et al. - Given that the occurrence of a major pulmonary complication is seen in 5% of adult patients undergoing noncardiac inpatient surgery, researchers investigated whether the choice of neuromuscular blockade reversal (neostigmine vs sugammadex) is related to a lower incidence of major pulmonary complications. They performed a multicenter observational matched-cohort analysis of surgical cases, in which, 12 US Multicenter Perioperative Outcomes Group hospitals participated. Participants were adults undergoing elective inpatient noncardiac surgical procedures, who received general anesthesia and endotracheal intubation as well as a nondepolarizing neuromuscular blockade agent and reversal. Findings revealed a clinically and statistically significant lower incidence of major pulmonary complications in relation to sugammadex use in a generalizable cohort comprising adult patients undergoing inpatient surgery at US hospitals.