Lee JK, et al. - Researchers investigated the impact of using linezolid instead of ethambutol on the proportion of sputum culture conversion at 8 weeks of treatment in patients with pulmonary tuberculosis via conducting a phase 2, multicentre, randomised, open-label trial including patients with pulmonary tuberculosis at the three affiliated hospitals to Seoul National University and National Medical Center (Seoul–Seongnam, South Korea). Findings revealed no higher rates of culture conversion at 8 weeks of treatment with short-term use of linezolid. However, safety analyses and the resistance profile suggested that linezolid has the potential utility for shortening treatment for drug-susceptible tuberculosis.