Study to reduce infection prior to elective cesarean deliveries (STRIPES): A randomized clinical trial of chlorhexidine
American Journal of Obstetrics and Gynecology May 15, 2020
Stone J, Bianco A, Monro J, et al. - Researchers sought to determine if the risk of surgical site infections by 6 weeks postoperatively reduces when chlorhexidine gluconate-impregnated cloths, vs placebo cloths, are applied the night before and morning of scheduled cesarean delivery. They conducted a single-center, double-blind, placebo-controlled trial including 1,356 patients; 682 were assigned to receive Sage 2% chlorhexidine cloths and 674 were assigned to receive Sage Comfort Bath fragrance-free cloths (placebo) to apply to 6 skin sites on the body (neck/shoulders/chest, arm pits/arms/hands, abdomen/groin, left leg/foot, right leg/foot, back/buttocks) the night before and after a shower the morning of scheduled cesarean delivery. No reduction in the risk of surgical site infection after scheduled cesarean deliveries was observed in correlation with preadmission use of chlorhexidine gluconate cloths vs placebo. Surgical site infections were low in those patients in whom the standard of care guidelines were followed.
-
Exclusive Write-ups & Webinars by KOLs
-
Daily Quiz by specialty
-
Paid Market Research Surveys
-
Case discussions, News & Journals' summaries