Storytelling to improve disease outcomes in gout (STRIDE-GO): A multicenter, randomized controlled trial in African American veterans with gout
BMC Medicine Nov 13, 2021
Singh JA, Joseph A, Baker J, et al. - Among African-Americans (AAs) with gout, a culturally appropriate gout-storytelling intervention was not better than attention control for improving gout results.
A total of 306 male AA veterans with gout were enrolled in this 1-year, multicenter, randomized controlled trial and were randomized to gout-storytelling intervention (n = 152) vs a stress reduction video (attention control group; 1:1 ratio) (n = 154); 261/306 (85%) completed the 1-year study.
Similar urate-lowering therapy adherence was noted between the intervention vs control groups.
At all time points, similar secondary outcomes (gout flares, serum urate and gout-specific health-related quality of life [HRQOL]) were observed between the intervention vs control groups.
The exception to this was better outcomes in the intervention group for the following: (1) fewer number of gout flares at 9 months; (2) lower/better scores on two gout specific HRQOL subscales: gout medication side effects at 3 months, 32.8 vs 39.6; and unmet gout treatment need at 3 months, 30.9 vs 38.2, and 6 months, 29.5 vs 34.5, respectively.
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