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Stereotactic radiosurgery for brain metastases: A retrospective cohort study comparing treatment results between two lung cancer patient age groups, 75 years or older vs 65–74 years

Lung Cancer Aug 21, 2020

Yamamoto M, Serizawa T, Sato Y, et al. - Researchers compared patients ≥ 75 (very elderly) with those who were 65−74 years old (elderly) in this IRB-approved retrospective cohort study to see if stereotactic radiosurgery (SRS) outcomes varied between the two patient groups. There were 2,915 elderly patients with lung cancer selected for the study from the researchers' own database of those undergoing gamma knife (GK) SRS for brain metastases. Significantly shorter median survival times (MSTs, months) after SRS were reported for NSCLC patients in the very elderly (9.7) group vs those in the elderly (7.8) group. However, no significant MST disparities between the two age groups were evident in patients suffering with SCLC. Based on the findings, experts concluded that in comparison with patients 65−74 years old, carefully-selected patients ≥ 75 years of age can be good candidates for SRS.

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