Cheung KS, et al. - Since statins have been shown to be associated with a lower risk of CRC, researchers ascertained if postcolonoscopy colorectal cancer (PCCRC) risk was also lower among statin users. Using a territory-wide electronic healthcare database in Hong Kong, patients (aged 40 years or more) who had undergone colonoscopies between 2005 and 2013 were included. Previous colorectal cancer (CRC), inflammatory bowel disease, prior colectomy, and CRC detected within 6 months of index colonoscopy were criteria for exclusion. Investigators found that PCCRC-3y (defined as cancer diagnosed between 6 and 36 months after index colonoscopy) was diagnosed in 854 of 187,897 eligible subjects. The results obtained from the retrospective cohort study indicate that statins were related to lower PCCRC risk, especially for proximal cancer. Data reported that a greater benefit was seen in older (>60 years) patients, women, and those without diabetes mellitus or polyps.