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Socioeconomic inequalities in prevalence and development of multimorbidity across adulthood: A longitudinal analysis of the MRC 1946 National Survey of Health and Development in the UK

PLoS Medicine Oct 08, 2021

Khanolkar AR, Chaturvedi N, Kuan V, et al. - Findings showed that socioeconomically disadvantaged people experienced earlier onset as well as more rapid accumulation of multimorbidity leading to broadening inequalities into old age, with independent contributions from both childhood and adulthood socioeconomic position (SEP).

  • This analysis involved participants from the UK 1946 National Survey of Health and Development birth cohort study.

  • Between ages 36 and 69 years, longitudinal multimorbidity trajectories were estimated, and if these trajectories differed by childhood and adulthood SEP was determined.

  • Throughout follow-up, there was 1.2 to 1.4 times greater number of health conditions on average in the most socioeconomically disadvantaged vs the most advantaged.

  • On average, increase in multimorbidity across adulthood and into older ages was seen in both socioeconomically disadvantaged and advantaged groups.

  • However, based on SEP, there was a difference in the rate at which multimorbidity increased across adulthood; worse trajectories were observed in those from the most disadvantaged backgrounds.

  • Childhood and adulthood SEP were identified to be independently related to multimorbidity across adulthood.

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