Bean MB, Liu Y, Jiang R, et al. - Researchers compared small cell carcinoma of the head and neck (SmCCHN) with squamous cell carcinoma of the head and neck (SCCHN) in terms of patient and tumor-related features as well as survival via utilizing data from the US National Cancer Institute's Surveillance, Epidemiology, and End Results database for 1973–2013. Overall, 609 SmCCHN and 227,943 SCCHN cases were analyzed. Men and white patients more commonly developed both histological subtypes. The likelihood of originating in the larynx, glottis and hypopharynx, or salivary glands was found to be greater in SmCCHN. For SCCHN, the most likely origin was the oral cavity, which showed an infrequent presence in the salivary glands. Furthermore, worse survival and greater possibility of presenting with more advanced stage were reported for SmCCHN vs SCCHN.